Table 1

Alcian blue and MCM staining in the duodenum of Apc+/−, p21+/+, +/−, or −/− mice fed AIN-76A diet

All mice Apc andNaTotal cells per columnb,cAlcian blueMCM
(+) cells(+) cells (%)(+) cells(+) cells (%)
p21 614.7 ± 0.61.72 ± 0.2211.71.66 ± 0.1811.3
p21 614.6 ± 0.21.38 ± 0.27d9.4d1.33 ± 0.40e9.2e
p21 614.8 ± 0.31.07 ± 0.18f7.2f1.13 ± 0.17f7.7f
  • a N, number of mice studied each group.

  • b Values are mean ± SD.

  • c Fifty crypt columns were counted in each mouse.

  • d P < 0.05,

  • e P = 0.06,

  • f P < 0.001, in comparison to the Apc+/−, p21+/+ mice (by Student’s t test).