Table 3

Correlations with p53 codon 72 polymorphisms in invasive cervical lesions of Swedish and Italian women

Correlation of HPV 16 E6 prototype and HPV 16 E6 variants of Swedish womena
PP/APb (%)AA (%)
ICC/Prototype6 /15 (40.0)9 /15 (60.0)
ICC/E6 variants19 /49 (38.8)30 /49 (61.2)
Correlation of HPV 16 E6 L83V and HPV 16 E6 other variants of Italian women
PP/APb (%)AA (%)
ICC/L83V5 /26 (19.2)21 /26 (80.8)
ICC/Other variantsc4 /11 (36.4)7 /11 (63.6)
  • a For 8 cases of ICC in the Swedish cohort, no E6 data were available. The p53 genotypes detected in these cases were AA (n = 7) and AP (n = 1).

  • b PP/AA, proline/arginine homozygotes; AP, heterozygotes.

  • c Other variants denote African-like and American-Asian multivariants (15 , 18) , H24Y and R10G/L83V.