Table 1

Independent age-, weight-, and ethnicity-adjusted RRsa and 95% CIs for breast cancer by CYP17 and HSD17B1 genotypes

Stage 1Advanced
ControlsCasesRR95% CICasesRR95% CI
CYP17
A1A1 5422221.00701.00
A1A2 7392870.950.77–1.181221.280.93–1.75
A2A2 2271061.080.81–1.44431.450.96–2.20
P for trend = 0.05
HSD17B1
GG 3691541.00451.00
GA 7392971.000.79–1.271261.390.96–2.00
AA 4001640.990.76–1.29641.280.85–1.93
P for trend = 0.28
Total1508615235
  • a Logistic regression model includes CYP17, HSD17B1, age, weight, and ethnicity.