Table 1

Patient characteristics

Patient no.Tumor pathologyAgePrevaccine RxAfter vaccination RxAdverse eventsSurvival (days)Time to progression (days)Time of additional surgeryIntratumoral T cellsPeripheral CTL
1AAa28HydroxyureaPolyIC632Negative
2GBM51ReoperationD381259264NegativePositive
3GBM48GliadelFever, nausea618
4GBM49Reoperation, SRTD463216224NegativePositive
5AA30PolyICLymph nodes550Positive
6GBM59Reoperation, SRT455105112PositivePositive
7GBM42574Pre-existing
8GBM55Reoperation, SRT31574/22281/232PositivePre-existing
9GBM77300
  • a AA, anaplastic astrocytoma; Gliadel, intracranial 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea; Poly IC, nonspecific immunotherapy; SRT, stereotactic radiation therapy; D, time of death.