Table 1

Genotype analysis of 86 patients with mutations in MMR genes at each of three NAT2 loci

NAT2 locusWT/WTaWT/MbM/MTotal Nc
NAT2*5 qd = 0.34 (56/168)39341184
NAT2*6 q = 0.30 (51/170)44311085
NAT2*7 q = 0.07 (11/168)7311084
  • a WT, wild type at NAT2 locus indicated in first column.

  • b M, mutant at NAT2 locus indicated in first column.

  • c Not equal to total number of subjects because we were unable to obtain genotypes for some. All of the subjects that were genotyped for each locus are presented in this table including both affected and unaffected subjects.

  • d q, allele frequency.