Table 2

Median time to diagnosis (years) for CRC and all of the cancers for all of the subjects stratified by NAT2 genotype and number of affected individualsa

CancerNAT2 locus(WT/WTb)(WT/Mc)(M/M)
CRC NAT2*5 50.0 (n = 21)48.0 (n = 22)36.0 (n = 5)
NAT2*6 47 (n = 24)57.1 (n = 17)46.7 (n = 8)
NAT2*7 53.6 (n = 42)46.7 (n = 6)(n = 0)
All cancers NAT2*5 48.0 (n = 25)48.0 (n = 22)43.0 (n = 6)
NAT2*6 42.0 (n = 27)57.0 (n = 19)42.0 (n = 8)
NAT2*7 48.0 (n = 46)39.5 (n = 7)(n = 0)
  • a n, number of affected individuals.

  • b WT, wild type at NAT2 locus indicated in second column.

  • c M, mutant at NAT2 locus indicated in second column.