Table 1

Summary of EphA2-overexpressing MCF-10A cells

The subcellular localization and P-Tyr content of EphA2 in control (vector) and EphA2-overexpressing MCF-10A cells are summarized. Also shown is a summary of the behaviors of the two cell types as measured in the presence of absence of soluble ligand (0.5 μg/ml EA1).
	Subcellular localization	P-Tyr content	Soft agar colonization	Behavior in 3dRBM^a
Vector	Cell-cell contacts	High	Negative	Benign
EphA2	Membrane ruffles	Low	High	Aggressive (stellate)
EphA2+EA1	Membrane ruffles	High	Low	Benign