Table 4

Correlations between different parameters evaluated given as Ps

LOHp53 IHCabcl-2 IHCbc-erbB-2 IHCc intensityTumor gradeTumor stage
IntensityIndexIntensityIndex
TP53 mutationsd0.021<0.001<0.0010.0030.003<0.0010.0010.219
TP53 mutationse0.056<0.001<0.0010.0050.0050.0010.0100.446
TP53 mutationsf0.0310.0100.0020.0020.002<0.0010.0250.552
LOH0.0720.0160.2300.2300.5240.1330.073
p53 IHC intensity0.1110.0530.0700.090
p53 IHC index0.1110.7060.0010.146
bcl-2 IHC intensity0.0010.1170.807
bcl-2 IHC index0.0010.1170.807
c-erbB-2 intensity0.3260.181
Tumor grade0.548
  • a p53 immunohistochemistry given as staining intensity and staining index.

  • b bcl-2 immunohistochemistry given as staining intensity and staining index.

  • c Membraneous c-erbB-2 immunostaining given as staining intensity.

  • d TP53 gene mutations grouped as wild-type versus all mutations.

  • e TP53 gene mutations grouped as mutations affecting the L2 or L3 domains versus mutations not affecting the L2 or L3 domains versus wild-type (three separate groups).

  • f TP53 gene mutations grouped as mutations affecting L2 or L3 domains versus wild-type plus TP53 gene mutations not affecting the L2 or L3 domains (two separate groups).