Table 3

Detection of CEA-specific mRNA by nested RT-PCR in peripheral blood cells vs. serum marker levels of colorectal cancer patients

StageNo. of patientsNo. of patients positive fora
CEA RT-PCRSerum CEAAny of the three serum markersbAny of the three serum markers and RT-PCRCEA RT-PCR and negative by all three serum markersAny of the three serum markers and/or RT-PCR
A62 (33.3)0 (0.0)1 (16.7)1 (16.7)1 (16.7)2 (33.3)
B159 (60.0)2 (13.3)3 (20.0)3 (20.0)6 (40.0)9 (60.0)
C87 (87.5)3 (37.5)4 (50.0)3 (37.5)4 (50.0)8 (100.0)
D1713 (76.5)11 (64.7)13 (76.5)10 (58.8)3 (17.6)16 (94.1)
Locoregional recurrence54 (80.0)2 (40.0)3 (60.0)3 (60.0)1 (20.0)4 (80.0)
Total5135 (68.3)18 (35.3)24 (47.1)20 (39.2)15 (29.4)39 (76.5)
  • a Values in parentheses are percentages.

  • b CEA, CA19.9, CA72-4.