Summary of the CEA RT-PCR results on blood samples from colorectal cancer patients undergoing chemotherapy
Patient | Stage | Site of metastasis | Days post surgery | CEA RT-PCR | Serum levelsa | Postsurgical treatment | ||
---|---|---|---|---|---|---|---|---|
CEA | CA19.9 | CA72-4 | ||||||
26 | C2 | −5 | ++ | 5.6 (+) | 0.4 (−) | 0.4 (−) | CHT-RTb | |
90 | + | 9.0 (+) | 18.4 (−) | 1.2 (−) | ||||
210 | + | 12.5 (+) | 29.3 (−) | 1.5 (−) | ||||
Lung | 420 | +++ | 793.8 (+) | 2319.0 (+) | 0.6 (−) | Lung metastasis | ||
Lung | 483 | +++ | 894.0 (+) | 1090.0 (+) | 1.8 (−) | |||
38 | D | Multiple | −2 | +++ | 10.2 (+) | 2.0 (−) | 0.1 (−) | CHT |
36 | ++ | 9.4 (+) | 0.1 (−) | 0.1 (−) | Stable disease | |||
53 | ++ | 16.2 (+) | 0.1 (−) | 1.8 (−) | Stable disease | |||
235 | ++ | 51.3 (+) | 0.1 (−) | 2.6 (−) | Stable disease | |||
319 | +++ | 82.0 (+) | 0.8 (−) | 2.4 (−) | PD | |||
530 | +++ | 573.1 (+) | 5.3 (−) | 3.3 (−) | PD | |||
31 | D | Liver | −1 | +++ | 311.6 (+) | 6490.1 (+) | 1.3 (−) | CHT |
33 | − | 224.0 (+) | 182.9 (+) | 2.4 (−) | ||||
51 | − | 60.5 (+) | 462.0 (+) | 2.6 (−) | Responsive | |||
182 | ++ | 226.5 (+) | 487.1 (+) | 42.6 (+) | PD | |||
37 | D | Liver | −1 | +++ | 13.5 (+) | 84.6 (+) | 22.5 (+) | CHT |
33 | − | 4.3 (−) | 45.3 (+) | 8.4 (+) | Responsive | |||
51 | − | 4.1 (−) | 39.5 (+) | 6.9 (+) | Responsive | |||
182 | ++ | 9.5 (+) | 76.4 (+) | 18.9 (+) | PD | |||
46 | D | Liver | −11 | +++ | 1.0 (−) | 0.4 (−) | 0.3 (−) | CHT |
41 | ++ | 1.4 (−) | 0.1 (−) | 1.4 (−) | Responsive | |||
56 | ++ | 2.2 (−) | 0.1 (−) | 0.4 (−) | CR | |||
219 | + | 1.1 (−) | 0.8 (−) | 2.1 (−) | CR |
a Serum CEA levels were determined by an enzyme immunoassay test kit, using a value of 5 ng/ml as positive. CA19.9 was determined using the CA19.9 kit with the suggested value 37 units/ml as positive. Serum CA72-4 antigen levels were determined using the CA72-4 kit with the suggested value 6 units/ml as positive.
b CHT-RT, chemotherapy + radiotherapy; PD, progressive disease; CR, complete remission.