Table 3

Univariate analysis

A. Urine VEGF
Survival analysisHR (95% CI)P
Baseline VEGF (>28 vs. H28 pg/ml)1.66 (1.06–2.59)0.03
15% reduction in VEGF D29 from baseline1.62 (1.01–2.62)0.05
Baseline VEGF (D1) (continuous)1.00 (1.00–1.01)0.07
Ratio D29:D1 VEGF (continuous)0.98 (0.95–1.01)0.11
Reduction in VEGF D29 from D1 (continuous)1.03 (0.99–1.06)0.11
Difference between VEGF D29 and D11.00 (0.99–1.06)0.15
Ratio D29:D1 VEGF (>1 vs. ≤1)0.75 (0.47–1.18)0.21
B. Urine bFGF
Ratio D29:D1 bFGF (>1 vs. ≤1)0.63 (0.38–1.07)0.08
bFGF (>0.5 vs. ≤0.5)1.39 (0.89–2.17)0.15
Baseline bFGF (D1) (continuous)1.02 (0.97–1.07)0.48
15% reduction in bFGF, D29 from D11.22 (0.68–2.19)0.50
Reduction in bFGF, D29 from D1 (continuous)1.00 (0.97–1.04)0.83
Ratio D29:D1 bFGF (continuous)1.00 (0.96–1.03)0.83
Difference between bFGF, D29 and D11.00 (0.95–1.05)0.97