Table 2

In utero chemical exposures and infant leukemia (OR,a 95% CI)

ExposurebTotal seriesMLL+ve subgroupMLL−ve subgroupALLAML
Smoking1.43 (0.86–2.39)0.98 (0.46–2.09)1.72 (0.74–3.99)f1.59 (0.82–3.07)1.33 (0.63–2.80)
(ca = 36, ct = 53)P = 0.17P = 0.97P = 0.21P = 0.17P = 0.45
Alcohol1.23 (0.68–2.23)0.74 (0.29–1.90)2.09 (0.91–4.84)f0.63 (0.25–1.60)1.92 (0.90–4.10)
(ca = 21, ct = 33)P = 0.50P = 0.54P = 0.08P = 0.33P = 0.09
DNA damaging drugs1.71 (1.03–2.84)2.31 (1.06–5.06)0.56 (0.18–1.80)f1.78 (0.95–3.34)2.28 (1.10–4.71)
(ca = 37, ct = 47)P = 0.039P = 0.036P = 0.33P = 0.07P = 0.026
Herbal medicines2.93 (1.57–5.48)3.00 (1.38–6.54)2.64 (1.04–6.67)f4.45 (2.06–9.63)2.09 (0.89–4.92)
(ca = 27, ct = 22)P = 0.001P = 0.006P = 0.04P < 0.001P = 0.09
Maternal pesticide3.67 (1.54–8.74)4.96 (1.71–14.43)1.87 (0.36–9.61)f2.53 (0.71–8.97)5.08 (1.84–14.04)
(ca = 15, ct = 10)P = 0.003P = 0.003P = 0.45P = 0.15P = 0.002
Dipyrone2.83 (1.15–6.99)5.84 (2.09–16.30)0.64 (0.08–5.41)3.13 (1.02–9.57)3.01 (0.93–9.79)
(ca = 12, ct = 9)P = 0.02P = 0.001P = 0.68P = 0.046P = 0.07
Baygon/mosquitocidal5.14 (1.27–20.85)9.68 (2.11–44.40)0 (0–15.19)4.30 (0.66–28.08)7.82 (1.73–35.39)
(ca = 7, ct = 3)P = 0.02P = 0.003P = 1.0P = 0.13P = 0.008
  • a ORs are for exposed compared with nonexposed.

  • b Numbers are for cases (ca) and controls (ct) exposed in the total series.