Table 1

p53 mutation analysis in ESCC patients from northern Iran, Tehran

No.Patient codeAge/Sex (yr)Tumor diagnosisp53 mutations
CodonBaseType
1TH-F9768/FSCC273CGT→TGT C→Tm,a CpG
2TH-F9868/FSCCNo mutationNA
3TH-F99NA/FSCC213CGA>TGA C→Ts, CpG
4TH-F10053/FSCCIntron 7G→Csp
5TH-F10157/MSCC196CGA→TGA C→Ts,CpG
6TH-F10259/FSCCNo mutationNA
7TH-F10327/MSCCNo mutationNA
8TH-F10570/FSCC242TGC→TTC G→Tm
9TH-F10664/FSCC203GTG→TTG G→Tm
10TH-F10772/MSCC248CGG→CAG G→Am, CpG
11TH-F10964/FSCC141TGC→TAC G→Am
12TH-F11168/FSCC213CGA→TGA C→Ts, CpG
13TH-F11265/MSCCNo mutationNA
14TH-F11376/MSCC237ATG→ATT G→Tm
15TH-F11460/FSCC248CGG→CAG G→Am, CpG
16TH-F11563/MSCC258GAA→AAA G→Am
282CGG→TGG C→Tm, CpG
17TH-F11658/FSCC229TGT→T del −2Frameshift
18TH-F11749/FSCC248CGG→TGG C→Tm, CpG
19TH-F11865/MSCC273CGT→CAT G→Am, CpG
20TH-F11971/MSCCIntron 5G→Asp
21TH-F12058/FSCCNo mutationNA
22TH-F12168/MSCCNo mutationNA
23TH-F12351/FSCCIntron 6G→Tsp
24TH-F12566/FSCCNo mutationNA
25TH-F12670/FSCC251ATC→AAC T→Am
26TH-F12765/FSCCNo mutationNA
27TH-F12874/FSCC212TTT→TT del −1Frameshift
28TH-F12964/MSCC213CGA→TGA C→Ts, CpG
29TH-F13042/MSCCNo mutationNA
30TH-F13160/FSCC168CAC→CGC A→Gm
31TH-F13227/FSCC296CAC→TAC C→Tm
32TH-F13329/MSCCNo mutationNA
33TH-F13462/FSCC196CGA→TGA C→Tm, CpG
147GTT→GTTGGGT ins+4Frameshift
34TH-F13558/FSCC191CCT→TCT C→Tm
302GGG→GAG G→Am
306CGA→TGA C→Ts, CpG
35TH-F13662/MSCC206TTG→TAG T→As
243ATG→TG del−1Frameshift
36TH-F13766/FSCCNo mutationNA
37TH-F13940/FSCCNo mutationNA
38TH-F14066/FSCCNo mutationNA
39TH-F 14174/FSCCIntron 5T→Csp
40TH-F14252/MSCC286GAA→AAA G→Am
  • a m, missense; del, deletion; ins, insertion; s, stop mutation; sp, splice mutation; CpG, CpG transition; NA, not available.