Table 2

p53 mutation analysis in ESCC patients from northern Iran, Caspian Littoral

No.Patient codeAge/Sex (yr)Tumor diagnosisp53 mutations
CodonBaseType
1Sa-F358/FSCC209AGA→Adela-2Frameshift
2Sa-F469/MSCC267CGG→CGdel-1Frameshift
3Sa-F571/MSCC286GAA→AAAG→Am
4Sa-F660/FSCCNo mutationNA
5Sa-F758/MSCC248CGG→TGGC→Tm, CpG
6Sa-F880/MSCCNo mutationNA
7Polsen-F11n54/MSCC265CTG→CGGT→Gm
8Nos-F1250/MSCC152CCG→CTGC→Tm, CpG
9Sa-F1664/MSCC254ATC→ATdel-1Frameshift
10Ghon-F2370/FSCC248CGG→TGGC→Tm, CpG
11Ghon-F2464/FSCCNo mutationNA
12Part-F2650/FSCC153CCC→CTCC→Tm
161GCC→GTCC→Tm
13Nek-F3174/MSCCNo mutationNA
14Sa-F3357/MSCCNo mutationNA
15Sa-F3869/FSCCNo mutationNA
16Nos-F1348/FSCC152CCC→CTGC→Tm, CpG
17Sa-F4179/FSCC178CAC→CAACins+1Frameshift
18Ba-F5155/MSCCNo mutationNA
19Sav-F5350/FSCC213CGA→TGAC>Tm, CpG
20Gham-F5472/MSCCNo mutationNA
21Ba-F5670/MSCCNo mutationNA
22Ba-F5777/FSCCIntron 7G→Tsp
23Ami-F5860/MSCC289–292del-8Frameshift
CTCCGGAAGAAA→CTAA
24Sa-F6766/MSCC248CGG→TGGC→Tm, CpG
25Sa-F6960/FSCC242TGC→TTTG→Tm
C→Tm
26Rod-F7569/FSCCNo mutationNA
27Gham-F7651/FSCC155ACC→ATCC→Tm
28Aghg-F8553/MSCC169ATC→ACGT→Cm
29Alia-F8645/FSCCNo mutationNA
30Gorg-F8780/MSCCNo mutationNA
31Khnb-F9142/MSCC127–134TCC . . . TTT→TTdel-22Frameshift
del.CCCCTGCCCTCAACAAGATGTT
32Gorg-F9241/MSCCNo mutationNA
33Sa-FII38/FSCC248CGG→TGGC→Tm,CpG
34Sa-FIII72/MSCC213CGA→TGAC→Tm,CpG
  • a del, deletion; ins, insertion; sp, splice mutation; m, missense; CpG, CpG transition; NA, not available.