Table 3

Association of abnormal expression of p16, p53, and K-ras codon 12 mutation in 106 NSCLCs

p53aPbK-ras codon 12Pb
NormalAbnormalWild-typeMutant
p16a Normal1122267
p16a Abnormal26470.8262110.44
  • a p16 was scored as positive nuclear staining (normal) or no nuclear staining (abnormal). p53 was scored as normal (no staining) or abnormal (nuclear staining).

  • b P was calculated by χ2 test.