Table 1

Immunohistochemical detection of BCRP using the BXP-21 and the BXP-34 Mabs and BCRP/PBGD mRNA expression ratios in human tumor cell lines

Tumor cell linesBXP-21BXP-34BCRP/PBGD
IGROV1a0.04
T8••••5
T8-revertant•/○•/○1
GLC4/ADR0.01
  • a ○, no staining; ••, strongly positive staining on plasma membrane; •/○, heterogeneous staining, i.e. approximately 15% of the cells positive on plasma membrane, all of the other cells negative.