Table 1

Group average weight changes for the eight experimental groups

Weights were obtained three times/week throughout the treatment course. The beginning and ending weights are shown, as well as the average change in grams and percentages.
CBHA (mg/kg)RA (mg/kg)Start weightaFinal weightaChange (%)b P c
0023.8 ± 0.7626 ± 0.842.2 (9)
02.526.1 ± 0.7726.3 ± 0.800.2 (0)0.04
50022.7 ± 0.8524.4 ± 0.711.7 (7)0.81
502.526.7 ± 1.0425.6 ± 0.75−1.1 (−4)<0.01
100028.2 ± 1.3427.9 ± 1.32−0.3 (−1)<0.01
1002.525.3 ± 0.6724.6 ± 0.58−0.7 (−2)<0.01
200027.1 ± 0.924.9 ± 0.79−2.2 (−8)<0.01
2002.527.2 ± 0.825.4 ± 0.78−1.8 (−6)<0.01
  • a All values are presented as the mean ± SE in grams for each treatment group. Initial and final body weights refer to the weight of the mice at the start of treatment and at the end of the study (day 21), respectively, with tumors in situ.

  • b Weight change is listed as the difference between the group mean final and the initial weights in grams with the percent change in parentheses.

  • c The P indicates whether the distribution of average weight change was significantly different from that of control. Derived by the nonparametric Wilcoxon rank-sum test.