Table 2

The effect of inhibition of the Ca2+-dependent proteolytic system on protein degradation in soleus muscle of control mice and those bearing the MAC16 tumor, with or without administration of EPA (2.5 g/kg)

AdditionProtein degradation (μmol tyrosine g−1 2 h−1)
CaC + EPAPbTaT + EPAPb
CaCl2459 ± 4410 ± 5NS618 ± 22516 ± 12<0.005
No Ca2+ + Inhibitor384 ± 2381 ± 21NS441 ± 6475 ± 7NS
P b <0.01NS<0.0050.05
  • a C, control mice; T, mice bearing the MAC16 tumor.

  • b NS, not significant; number of animals; C, n = 6; T, n = 8. Control and tumor-bearing groups were run concurrently.