Table 2

Estimated IC50 values in H526 SCLC cells

CompoundIC50m)
SCF-stimulated growthFBS-stimulated growthaSCF-induced Kit activation
SU54161.913.10.01
SU5614NDaNDa0.05
SU66688.522.10.73
SU65974.519.40.08
SU66637.423.80.48
SU656115.024.00.25
  • a FBS, fetal bovine serum; ND, not determined.