Table 1

Detection of HCMV proteins in different-grade gliomas, meningiomas, other CNS diseases, and normal brain

Results from IHC with antibodies to four HCMV proteins and CD34 are shown. Anti-IE1-72 antibody was reactive with HCMV-positive control tissues and nonreactive with HSV-1-infected tissue (not shown).

SpecimenmAb specific for
IE1-72pp65p52/76kD IE/EACD34a
Glioblastoma22/228/88/80/22
Grade III oligoastrocytoma1/10/1
Grade II astrocytoma4/42/22/20/4
Normal brain0/50/10/5
Meningioma0/9
Stroke0/4
Alzheimer’s0/3
Paraneoplastic encephalitis0/1
Cryptococcal cerebritis0/1
  • a Immunoreactivity was present in blood vessels only.