Table 2

CAR membrane staining of normal prostate, prostate carcinoma, and metastatic disease

A. Distribution of CAR staining intensity by tumor grade
GradeNumberIntensity
01+2+3+
Normal33528 (85%)
Low293197 (24%)
Intermediate241311 (46%)
High231166 (26%)
Androgen independent2012170
Metastatic disease99 (100%)
B. Percentage of cells stained with CAR by tumor grade and intensity
No.Total3+ intensity0–2+ intensity
Mean % (range)No.Mean % (range)No.Mean % (range)
Normal33100% (100%)28100% (100%)5100% (100%)
Tumor grade
 Low2971% (40–100%)780% (70–100%)2268% (40–100%)
 Intermediate2477% (50–100%)1185% (70–100%)1370% (50–90%)
 High2363% (5–100%)683% (40–100%)1757% (0–100%)
 Androgen independent2052% (0–100%)02052% (0–100%)
Metastatic disease972% (10–100%)972% (10–100%)