Table 2

Single nucleotide polymorphisms of the hMSH2 and hMLH1 promoters in nonmalignant controls, cases of HNPCC, suspected cases of HNPCC, and sporadic early onset colorectal cancer patients

Frequency (%)
hMSH2 (−118)hMLH1 (−93)
C/CC/TT/TG/GG/AA/A
Control (n = 157)3.330.366.426.747.326
ICG-HNPCC (n = 40)029.170.8164044
S-HNPCC (n = 56)040.659.3313831
Early CRCb (n = 45)029.670.3235323
  • a Suspected HNPCC patient.

  • b Sporadic early-onset colorectal cancer patient.