Table 3

Stratification analysis of DNMT3B genotype frequencies, ORs, and 95% CIs

Adjusted OR (95% CI)a
CC (ref.)CT OR (95% CI)TT OR (95% CI)CT/TT OR (95% CI)
Total1.002.13 (1.47–3.08)1.42 (0.91–2.21)1.88 (1.32–2.66)
Age (yr)
 <601.002.90 (1.64–5.13)1.50 (0.77–2.91)2.34 (1.37–4.00)
 ≥601.001.72 (1.05–2.82)1.41 (0.77–2.60)1.62 (1.02–2.59)
Sex
 Male1.001.54 (0.95–2.50)1.18 (0.64–2.16)1.42 (0.90–2.25)
 Female1.003.30 (1.84–5.93)1.88 (0.96–3.65)2.72 (1.57–4.71)
Histology
 Adenocarcinoma1.001.84 (1.17–2.91)1.41 (0.82–2.42)1.69 (1.10–2.60)
 Squamous cell carcinoma1.003.21 (1.50–6.83)2.03 (0.82–5.03)2.81 (1.35–5.85)
 Non-small cell carcinoma1.002.09 (1.04–4.23)1.14 (0.46–2.85)1.77 (0.90–3.50)
 Small cell carcinoma1.001.67 (0.59–4.72)1.33 (0.38–4.63)1.55 (0.58–4.14)
 Others1.002.35 (0.70–7.92)1.24 (0.29–5.33)1.90 (0.60–6.03)
  • a Adjusted for age, sex, pack-years smoked, and family history of cancer within the strata.