Table 1

Summary of all injections performed with KRas and Akt in Ntv-a and Gtv-a wt and Ink4a-Arf−/− mice

tv-a strainGenetic backgroundOncogene(s)Glioma incidence
Ntv-a wt KRas 0 of 27
Ntv-a wt Akt 0 of 33
Ntv-a wtKras + Akt16 of 74
Ntv-a Ink4a-Arf −/− KRas 9 of 27
Ntv-a Ink4a-Arf −/− Akt 0 of 31
Ntv-a Ink4a-Arf −/− Kras + Akt21 of 43
Gtv-a wt KRas NDa
Gtv-a wt Akt ND
Gtv-a wtKras + Akt0 of 68
Gtv-a Ink4a-Arf −/− KRas 10 of 30
Gtv-a Ink4a-Arf −/− Akt 0 of 29
Gtv-a Ink4a-Arf −/− Kras + Akt13 of 31
  • a ND, not done.