Table 3

Association between chromosome-specific and genome-wide LOHa

Chromosome+ LOH− LOH
Meanb (n)SDMean (n)SD
12c4.13d (8)2.422.16 (12)1.70
 42.33 (18)1.812.44 (18)2.04
143.50d (12)2.431.83 (24)1.31
  • a Student’s t test (two-tailed) comparing frequencies of global LOH in tumors with and without LOH on specified chromosomes.

  • b Mean number of chromosomes with LOH per tumor.

  • c Analysis of chromosome 12 used carcinogen-induced tumors only. Analyses of chromosomes 14 and 4 used tumors from all treatment groups. Data are taken from Fig. 2 <$REFLINK> .

  • d P < 0.05.