Table 2

Allelic loss in leukoplakia that developed into SOM compared to that which did not

SOM (%) (n = 36)Non-SOM (%) (n = 32)P
No. with LOHa35 (97)15 (47)0.0001
>1 arm lost26 (72)9 (28)0.0006
LOH on 3p22/35 (63)b3/32 (9)b0.0001
LOH on 9p28/36 (78)9/32 (28)0.0001
LOH on 4q12/30 (39)1/26 (4)0.0014
LOH on 8p13/36 (36)6/32 (19)0.18
LOH on 11q6/32 (19)1/31 (3)0.10
LOH on 13q4/32 (13)2/30 (7)0.67
LOH on 17p13/36 (36)9/32 (28)0.61
LOH on 3p and/or 9p (but no other arms)11/36 (31)3/32 (9)0.039
LOH on 3p and/or 9p (plus LOH at any other arm)24/36 (67)7/32 (22)0.0003
All cases with LOH on 3p and/or 9p35/36 (97)10/32 (31)0.0001
  • a A total of seven chromosomal arms were tested. Values in parentheses are percentages.

  • b Loss/informative cases (% loss).