Table 1

Fisher’s exact tests for association between aberrant gene expression and clinicopathological features

mRNA levelsER-LB statusPgR-LB statusS-phase fractionDNA ploidy
PosaNegPPosNegPLowIntHighPDiAneuP
ERα
 Normal283751464
 High1721901134109
 Very high90<0.000190<0.00015130.88450.91
ERβ
 Low112010020
 Normal26427318481515
 High141411323
 Very high010.002100.0051000.53100.66
EGFRb
 Typical27530218591616
 > typical150.003150.00023021.00420.66
EGFR
 Very low14115081678
 Low1471651244129
 Normal020.012020.0031010.51110.86
ErbB2
 Normal25728418491814
 High313130113
 Very high020.11020.0290110.35110.65
ErbB3
 Low031230030
 Normal21723516291513
 High700.005700.0602320.10250.19
ErbB4
 Low141421232
 Normal15618312261110
 High1200.0021200.0027230.86661.00
ERRαb
 < typical101010110
 Typical26528318471615
 > typical150.003240.0062130.54331.00
ERRα
 Low335140151
 Normal2570.312661.00175100.6615170.18
ERRβ
 Low505011214
 Normal22824618471812
 High111110102
 Very high010.12100.381000.61100.069
ERRγ
 Normal455432345
 High19320212371012
 Very high510.054600.0456000.21600.042
  • a Pos, positive; Neg, negative; Int, intermediate; Di, diploid; Aneu, aneuploid.

  • b Expression levels relative to other tumors, not MECs.