Table 3

Spectrum of KRAS mutation in 70 colorectal cancers, 32 sporadic adenomas, and 5 FAP adenomas

Nucleotide changeAmino acid changeNo. of CRCsNo. of adenomasNo. of FAP adenomas
G35A G12D 21142
G35T G12V 1561
G34A G12S 4
G34T G12C 31
G35C G12A 21
G34C G12R 1
G38A G13D 195
G37T G13C 21
C64A Q22K 1
C176A A59E 1
G175A A59T 1
A182G Q61R 1
A183T, A183C Q61H 22
G274T D92Y 1