Table 2

Demographic and smoking data compared with methylation status of the different genes

All subjectsp16DAPKGSTP1
MaUMUMU
Subjects, n10017831783694
Age (yr)
 Median56585663555556
 Range35–7845–7035–7848–7135–7840–6035–78
 Mean ± SD56.6 ± 9.658.6 ± 756.2 ± 1061.5 ± 6.955.6 ± 9.853 ± 7.756.8 ± 9.7
Gender
 Male54945846252
 Female46838937442
Race
 White891673137660
 Others11110478311
Cancer history
 Yes9453609
 No9113781477685
Smoking status, median (range)
 Packs per day2 (0.8–4)1.5 (1–2.5)2 (0.8–4)1.5 (0.8–3)2 (1–4)1 (1–2.5)2 (0.8–4)
 Smoking years26.5 (11–50)26 (15–49)27 (11–50)32 (15–49)26 (11–50)26 (20–38)26.5 (11–50)
 Pack-years42 (20–136)35 (20–95)42 (20–136)42 (22–120)42 (20–136)29 (20–95)42 (20–136)
 Quitting years10.2 (1–48.1)10 (1.2–35.2)10.2 (1–48)9.7 (1.5–35.2)10.2 (1–48.1)2.6 (1.1–23.2)10.2 (0.9–48.1)
  • a M, methylated-specific primers; U, unmethylated-specific primers.