Table 4

Performance of BRCA1 classifiers

Summary of the best LOOCV performance and associated region sets for classification of BRCA1 tumors. Results are shown for the wrapped discrete SBC, as well as for the mutual information filtered SBC for both discrete and continuous representations. Only region sets where limited variation occurred in the selected sets (across the LOOCV loops) are listed.

Wrapped discrete SBCMutation information filtered SBC
RegionsPerformance (%)RegionsPerformance (%)
Discrete representation
Arms3q and 10p793q and 10p73
Bandsa3.5 and 5.2 and (2.1 or 10.2 or 3.1)773.1 and 3.5 and 5.284
Channels11 regions6416 regions67
Continuous representation
ArmsNot applicableNot applicable
Bandsa9 regions673.5 and 5.276
ChannelsToo computationally expensive5.31 and 5.3277
  • a 0.85VAF bands.