Performance of BRCA1 classifiers
Summary of the best LOOCV performance and associated region sets for classification of BRCA1 tumors. Results are shown for the wrapped discrete SBC, as well as for the mutual information filtered SBC for both discrete and continuous representations. Only region sets where limited variation occurred in the selected sets (across the LOOCV loops) are listed.
Wrapped discrete SBC | Mutation information filtered SBC | |||
---|---|---|---|---|
Regions | Performance (%) | Regions | Performance (%) | |
Discrete representation | ||||
Arms | 3q and 10p | 79 | 3q and 10p | 73 |
Bandsa | 3.5 and 5.2 and (2.1 or 10.2 or 3.1) | 77 | 3.1 and 3.5 and 5.2 | 84 |
Channels | 11 regions | 64 | 16 regions | 67 |
Continuous representation | ||||
Arms | Not applicable | Not applicable | ||
Bandsa | 9 regions | 67 | 3.5 and 5.2 | 76 |
Channels | Too computationally expensive | 5.31 and 5.32 | 77 |
a 0.85VAF bands.