Table 1

Patients’ characteristics and expression of Ang-1 and -2

All patients na (%)Expression of Ang-1 and Ang-2
Positive expression of Ang-1Positive expression of Ang-2
n (%)Pn (%)P
Total236 (100%)101 (42.8%)40 (16.9%)
Ageb
 Lower age (<64 yr)116 (49.2)49 (42.2%)0.89617 (14.7%)0.389
 Higher age (≥64 yr)120 (50.8)52 (43.3%)23 (19.2%)
Sex
 Male170 (72.0)67 (39.4%)0.10728 (16.5%)0.847
 Female66 (28.0)34 (51.5%)12 (18.2%)
Performance status (PS)
 0206 (87.3)88 (42.7%)36 (17.5%)
 128 (11.9)12 (42.9%)0.9793 (10.7%)0.306
 22 (0.8)1 (50.0%)1 (50.0%)
Histological type
 Sq85 (36.0)35 (41.2%)0.486 (Sq vs. Ad)16 (18.8%)0.304 (Sq vs. Ad)
 Ad130 (55.1)60 (46.2%)20 (15.4%)
 Large cell13 (5.5)1 (7.7%)1 (7.7%)
 Others8 (3.4)5 (62.5%)3 (37.5%)
Tumor cell differentiationc
 Well differentiated81 (35.2)32 (39.5%)7 (8.6%)
 Moderately differentiated91 (39.6)45 (49.5%)0.21921 (23.1%)0.039
 Poorly differentiated58 (25.2)21 (36.2%)10 (17.2%)
Pathological stage
 I138 (58.5)59 (42.8%)19 (13.8%)
 II44 (18.6)12 (46.2%)0.9245 (19.2%)0.285
 IIIa54 (22.9)30 (41.7%)16 (22.2%)
  • a n, number of patients.

  • b Age (mean ± SD), 62.4 ± 9.7 years.

  • c Other histological types were excluded in the analysis.