Table 1

Association between loss of Wnt-5a protein expression and clinicopathological features of invasive ductal carcinomas (1998/99)

No.Weak (+/−)Normal (+++/++)P
Age
 <50725
 ≥505224280.45
Histological grade
 I13 (22%)3 (23%)10 (77%)
 II24 (41%)9 (38%)15 (62%)
 III22 (37%)14 (64%)8 (36%)0.01
ERa
 Negative1311 (85%)2 (15%)
 Positive3612 (33%)24 (67%)0.003
PgRa
 Negative2114 (67%)7 (33%)
 Positive289 (32%)19 (68%)0.02
Tumor Size
 T1 ≤20 mm3012 (40%)18 (60%)
 T2 >20 ≤ 50 mm2212 (55%)10 (45%)
 T3 >50 mm72 (29%)5 (71%)0.96
Lymph node statusa
 Negative3414 (41%)20 (59%)
 Positive2512 (48%)13 (52%)0.79
  • a All tumors were not subjected to all of the indicated analyses.