Table 1

Numbers of genes showing significant correlation with sensitivity to nine anticancer drugsa

All xenografts (85)NSCLC (11)Breast cancer (14)Gastric cancer (13)
5FU2401846972
ACNU29015178101
ADR283729493
CPM45916810392
DDP21716676100
MMC321137199102
MTX2199275171
VCR244200107112
VLB21020110960
  • a These genes were identified not only in 85 xenografts but also in xenografts from NSCLC, breast cancer, and gastric cancer in order to explore the genes related to tissue-dependent chemosensitivity. These genes satisfied the following criteria: P < 0.01, and the absolute value of the slope of the regression line was larger than 1.5 between the 100-T/C range (see “Materials and Methods”).