Table 1

Comparison of papilloma incidence, papilloma burden, and tumors >1.5 mm in diameter per mouse during different periods of TPA treatment for wild-type and Jnk1−/− mice

Experimental details are described in the legend of Fig. 2 <$REFLINK> .

GroupPapilloma incidence weeks 13–33aPapillomas/mouse weeks 21–33Tumors (>1.5 mm)/mouse weeks 27–33
Wild-type68 ± 5b3.03 ± 0.112.63 ± 0.03
Jnk1 −/− 83 ± 54.11 ± 0.463.95 ± 0.43
P value<0.04<0.05<0.03
  • a First significant difference was observed after 13, 21, or 27 weeks of TPA treatment for papilloma incidence, papillomas/mouse, or tumors (>1.5 mm)/mouse, respectively.

  • b Mean ± SE. P indicates a statistically significant difference between wild-type and Jnk1−/− mice.