Table 2

Summary of tumor development at 33 weeks of TPA treatment for wild-type and Jnk1−/− mice

Experimental details are described in the legend of Fig. 2 <$REFLINK> .

GroupPapilloma incidencePapillomas/mouseTumors (>1.5 mm)/mouseCarcinoma incidenceCarcinomas/mouse
Wild-type87%3.4 ± 0.7a2.7 ± 0.553%1.8 ± 0.3
Jnk1 −/− 95%5.7 ± 0.84.8 ± 0.777%2.4 ± 0.3
  • a Mean ± SE. The difference in papillomas/mouse and tumors (>1.5 mm)/mouse between wild-type and Jnk1−/− mice was statistically significant at P <0.03.