Table 3

Estimated RR of hOGG1 SNPs for prostate cancer (Caucasians only)

SNPsGenotypeRR (95% CI),a FET P
SporadicHereditaryEither type of prostate cancer
6803C/G (Ser326Cys) GG 111
CC 3.23 (1.19–8.73)2.07 (0.65–6.62)2.72 (1.17–6.32)
FET P = 0.02FET P = 0.21FET P = 0.02
7143A/G AA 111
GG 5.12 (1.12–23.25)8.19 (1.51–45.45)5.21 (1.18–22.73)
FET P = 0.03FET P = 0.06FET P = 0.03
11657A/G AA 111
GG 9.80 (1.25–76.92)13.89 (1.57–125.00)9.80 (1.30–76.92)
FET P = 0.008FET P = 0.02FET P = 0.009
  • a Adjusted for age.