Table 4

Relationship between hpyIIIR or hrgA-containing H. pylori strains and clinical outcomes of 202 source patientsa from whom strains were isolated

LocalityWestern strainsAsian strains
hpyIIIR (n = 31)hrgA (n = 33)hpyIIIR (n = 104)hrgA (n = 34)
Clinical characteristics
 Median age, yr (range)56 (40–68)57 (43–67)58 (42–69)58 (40–72)
 African-American (%)121400
 M:F25:624:781:2326:8
 Gastric cancer (n = 43)0025b18b
 Nongastric cancer (n = 159)313379b16b
 Duodenal ulcer (n = 55)69346
 Gastric ulcer (n = 42)56256
 NUDc (n = 62)2018204
  • a For 6 of the original 208 strains, clinical data were not available.

  • b Among Asian strains, hrgA frequency in nongastric cancer cases (16 of 95; 17%) is significantly lower (P < 0.001) than in gastric cancer cases (18 of 43; 42%).

  • c NUD, nonulcer dyspepsia.