Table 5

Effect of H. pylori strains on AGS cells, according to hrgA or hpyIIIR genotypea

CriterionMean ± SDPb
hpyIIIR (n = 42)hrgA (n = 20)
IL-8 induction (pg/ml)1255 ± 6961291 ± 5950.83
Fold increase in DNA fragmentationc1.8 ± 1.41.5 ± 1.10.34
  • a H. pylori cells were cocultured with AGS cells at a ratio of 1000:1 and incubated for 24 h for the IL-8 induction assay, and at a ratio of 100:1 for 48 h of incubation in the DNA fragmentation assay.

  • b Based on paired t test.

  • c Relative to controls.