Table 2

Summary of expression levels of 10 chromosome 17q12-q21 transcripts in eight xenografts and three cell lines of gastric cancer by cDNA microarraya

GeneUnigene IdAccessionAlignmentbLocusbSamples
X43X49X57X68X75X76X80X95CRL- 5822CRL- 5973CRL- 5974
Adaptor-related protein complex 2, β1 subunit (AP2B1)Hs. 74626H299273732770017q121.112.9 3.1 0.91.10.90.8 4.8 7.4 4.6
EST (Hypothetical protein FLJ20940)Hs. 286192AA5525094186858417q21.1 21.9 4.5 6.4 7.6 10.2 10 17.3 0.6 12.1 11.2 0.6
V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2)Hs. 323910AA4469284194022917q21.111 3 3.7 1.40.91.30.7 24.6 0.71
Topoisomerase (DNA) II α (170kD) (TOP2A)Hs. 156346AA0266824252125417q21.2 4.1 6.1 16 4.5 2.8 6.6 3 1.4 5.6 7.6 6.8
Keratin 14 (KRT14)Hs. 117729H441274375714317q21.2 3.9 1.41.11.6 3.5 11.20.6 3.8 1.30.8
Junction plakoglobin (JUP)Hs. 2340R064174399496217q21.2 3.1 2.80.91.2 4.3 0.92.6 3.4 5 1.92.5
Amine oxidase, copper containing 3 (AOC3)Hs. 198241T773984507806617q21.2 4.6 1.9 4.5 2.62.12.6 4.2 1.6 3.1 1.8 5
Integrin, α-3 (ITGA3)Hs. 265829AA4246955468814017q21.3 4.8 1.50.9 4.5 3.4 1.31.11.22.72.20.5
ESTHs. 56105AA2842626581733417q23.211.7 5.2 3 15.6 2.80.61.91.30.60.4
Growth factor receptor-bound protein 2 (GRB2)Hs. 296381AA4498318184074217q25.10.80.82.21.41.31.81.11.3 3.1 5.6 3.5
  • a Expression ratios above the 3 threshold are shown in bold.

  • b Alignment (bp position) and locus are shown according to Santa Cruz August freeze 2001 assembly.