Table 1

DD3 expression in normal tissues

TissuerRNAa (×108)DD3aNormalized DD3b
Skin4.800
Skeletal muscle48.000
Heart12.000
Lymph gland26.000
Spleen38.000
Bone marrow4.600
Lung12.000
Stomach20.000
Ileum13.000
Colon16.000
Liver40.000
Pancreas24.000
Testis28.000
Bladder34.000
Kidney52.03908
Uterus44.000
Thyroid gland2.800
Brain14.000
Esophagus7.200
Ovaries7.800
Breast0.600
Prostate4.6699152
Leukocytes34.000
  • a Ct values were transformed to absolute gene copy numbers by calibration curves (5-log range) of rRNA and DD3 plasmid calibrators. The functions of the calibration curves were: f(CtrRNA) = −3.40 log [rRNA copies/20] + 40.80; and f(CtDD3) = −3.84 log [DD3 copies] + 45.32.

  • b Normalized DD3 = (DD3/rRNA) × 108.