Table 4

Decreased risk (aOR) of breast cancer development associated with a history of full-term pregnancy, stratified by the number of putative high-risk genotypes of NHEJ genes

Pregnancy historyaOR (95% CI)a
≤1 high-risk genotype>1 high-risk genotype
Having one additional full-term pregnancy0.83 (0.71–0.98)0.92 (0.83–1.03)
No. of full-term pregnancies
 01.00 (Ref.)b1.00 (Ref.)b
 1–20.45 (0.16–1.23)0.65 (0.35–1.23)
 ≥30.27 (0.09–0.83)0.53 (0.26–1.06)
  • a The aOR of breast cancer development associated with having one additional full-term pregnancy or the number of full-term pregnancies was calculated in a multivariate logistic regression model containing age, family history of breast cancer, BMI, and the number of full-term pregnancies or a set of dummy variables to represent groups with different numbers of full-term pregnancies.

  • b Ref., reference group.