Table 3

Effects of POH on preneoplastic lesion development

Esophagi were fixed, sectioned, and stained with H&E. Esophagi from 6 animals within each group were chosen randomly. Sections were evaluated under ×200 magnification, and each field was classified as either normal, hyperplastic, or dysplastic.

Group12345
Normal fields102 (62.2%)273 (34.3%)160 (64.8%)240 (27.1%)322 (35.4%)
Hyperplastic fields61 (37.2%)398 (50.0%)75 (34.8%)430 (48.6%)388 (42.6%)
Dysplastic fields1 (0.6%)125 (15.7%)1 (0.4%)214 (24.3%)a200 (22.0%)a
  • a Significantly higher than NMBA control (group 2).