Table 3

Effect of AKT2 expression on long-term survival postinvasion

MDA-MB-435 control cells and MDA-MB-435AKT2C23 cells were plated onto Matrigel-coated invasion chambers. The number of cells invading and surviving were counted 2 weeks and 4 weeks postinvasion. P are given in parentheses.

Cell linesTimeNo. of cells surviving postinvasion
MDA-MB-435 control2 wk20 ± 5.1
4 wk9 ± 5.7
435AKT2C232 wk199 ± 53 (P = 0.04)
4 wk2261 ± 377.6 (P = 0.01)