Genotype analysis of the human GPx-1 polyalanine polymorphism in breast cancer samples and cancer-free individuals
DNAs were genotyped to determine the number of alanine codon repeats in the gene for human GPx-1 as described in the text, and the data presented in the table represent the determined genotypes for individuals analyzed.
| GPx-1 (no. of Ala repeats) | Cancer-free (n = 109) | Breast cancer (n = 74) |
|---|---|---|
| 5/5 | 20 | 23 |
| 6/6 | 6 | 17 |
| 7/7 | 1 | 5 |
| Homozygosity | 24.8% | 60.8% |
| 5/6 | 38 | 12 |
| 5/7 | 33 | 9 |
| 6/7 | 11 | 8 |
| Heterozygosity | 75.2% | 39.2% |