Table 2

Viral yield of dl331 and Adwt in normal human cells

VectorHuman hepatocytesHuman fibroblasts
Meana (pfu/ml)SDMean (pfu/ml)SD
Ad-wt1,9.1076,0.1061,8.1073,3.106
dl3312,5.105b5,7.1041,1.106b2,3.105
ratio dl331/Ad-wt0,0130,06
  • a Mean yield values for the indicated virus determined from cell lysates obtained at day 4 postinfection by plaque assay.

  • b P < 0.005 versus Ad-wt yield by Student’s t test.