Table 4

Somatic LOH at chromosome 1p and 11q in 33 apparently sporadic phaeochromocytomasa

SDHB locus LOH chromosome 1pPSDHD locus LOH chromosome 11qP
++
According to the phenotype
 Adrenal (n = 21)138147
 Extra-adrenal + malignant (n = 12)48P = 0.12120P = 0.03
According to the SDHB mutation
 SDHB negative (n = 26)179197
 SDHB positive (n = 7)07P = 0.00261P = 0.49
  • a Differences in distributions were assessed by Fisher’s exact test.