Table 1

Overview of all SIs determined by [3H]thymidine incorporation

Survival times are in days and the results of the performed necropsies are indicated. Animals that died prematurely before 110 days after tumor implantation (Impl.) are marked with †; animals that were sacrificed after reaching the defined endpoint of 110 days according to the protocol are marked with E.

Animal group and no.SI before Impl.SI 1 wk after Impl.SI 2 wk after Impl.SI 4 wk after Impl.SI 6 wk after Impl.Survival in days after tumor implantationLocal recurrence/vital tumorMetastases, number/localization
Control group
 C11.101.461.4522 †YesMultiple/Peritoneum, Lungs
 C21.140.871.4622 †YesMultiple/Peritoneum, Lungs
 C31.49nd1.3820 †YesMultiple/Peritoneum, Lungs
 C41.511.170.641.3229 †YesMultiple/Peritoneum, Lungs
 C50.841.111.0229 †YesMultiple/Peritoneum, Lungs
 C60.691.281.281.140.9950 †YesMultiple/Peritoneum, Lungs
 C71.140.561.431.201.3458 †YesMultiple/Peritoneum, Lungs
 C80.960.610.541.3636 †YesMultiple/Peritoneum, Lungs
 C91.041.220.8222 †YesMultiple/Peritoneum, Lungs
RF group
 T11.261.1725.05100.8330.38110 ENoNo
 T21.070.9991.2371.7044 †YesMultiple/Peritoneum, Lungs
 T30.890.41152.7136.5441 †YesMultiple/Peritoneum
 T41.321.1158.7771.0626.2563 †YesMultiple/Peritoneum
 T50.840.9237.1057.1312.1663 †No2/Peritoneum
 T61.931.1258.2025.1395.3663 †NoMultiple/Peritoneum
 T71.630.7817.196.8319.2463 †YesMultiple/Peritoneum, Lungs
 T80.750.7019.945.0371.7069 †No2/Peritoneum
 T91.230.72108.3781.8160.97110 ENo4/Peritoneum
 T101.081.198.279.1854.13110 ENoNo
 T110.931.1318.62206.9752.18110 ENoMultiple/Lungs, (Peritoneum)