Prognostic value of EGFR gene status by univariate and multivariate analysis in older vs. younger groups according to age thresholds
| Age group | Median OS, yrs (no. of cases) | Univariate P | Multivariate (Amp. vs. no amp.) | ||
|---|---|---|---|---|---|
| Amp.a | No amp.b | HR (95% CI)d | P | ||
| 55 yrsc | |||||
| Older (n = 42) | 0.931 (21) | 0.901 (21) | 0.71 | nse | |
| Younger (n = 45) | 1.374 (19) | 2.324 (26) | 0.0040 | 2.72 (1.34–5.50) | 0.0054 |
| 60 yrsc | |||||
| Older (n = 27) | 1.262 (10) | 0.865 (17) | 0.53 | ns | |
| Younger (n = 60) | 1.133 (30) | 2.324 (30) | 0.0002 | 3.15 (1.69–5.89) | 0.0003 |
a Amplification.
b No amplification.
c Age threshold.
d CI, confidence interval.
e ns, not significant.