Table 7

Prognostic value of EGFR gene status by univariate and multivariate analysis in older vs. younger groups according to age thresholds

Age groupMedian OS, yrs (no. of cases)Univariate PMultivariate (Amp. vs. no amp.)
Amp.aNo amp.bHR (95% CI)dP
55 yrsc
Older (n = 42)0.931 (21)0.901 (21)0.71nse
Younger (n = 45)1.374 (19)2.324 (26)0.00402.72 (1.34–5.50)0.0054
60 yrsc
Older (n = 27)1.262 (10)0.865 (17)0.53ns
Younger (n = 60)1.133 (30)2.324 (30)0.00023.15 (1.69–5.89)0.0003
  • a Amplification.

  • b No amplification.

  • c Age threshold.

  • d CI, confidence interval.

  • e ns, not significant.