Table 1

Kinase, and cell potency and selectivity

Kinase (IC50, nm)Cell proliferation (IC50, nm)
VEGFR-21114
bFGF953
Tie-248NDa
PDGFrβ2,820ND
EGFR6,250ND
IGF-1R>10,000ND
  • a ND, not determined.