Table 1

Structures of C75, C273, and TOFA

StructureMolecular weightFatty acid synthesis inhibition (IC50)Cytotoxicity (LD50)
Embedded Image 25410.8 ± 2.7 μg/ml10.7 ± 2.2μ g/ml
Embedded Image 255Negative>80 μg/ml
Embedded Image 3244.0 ± 2.0>20 μg/ml